Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.

CONCLUSION: The kinetics of insulin following discontinuation of high-dose insulin therapy are largely unknown, but supraphysiologic insulin levels persist for some time following therapy; this may allow for simple discontinuation rather than titration of insulin at the end of therapy. Dextrose replacement is frequently needed; although the duration is often difficult to predict, prolonged infusions may not be necessary.
PMID: 32656624 [PubMed - as supplied by publisher]

Source: Journal of Medical Toxicology - July 10, 2020 Category: Toxicology Authors: Corcoran JN, Jacoby KJ, Olives TD, Bangh SA, Cole JB Tags: J Med Toxicol Source Type: research