Metabolic profiling of senkyunolide A and identification of the metabolite in hepatocytes by ultra-high performance liquid chromatography combined with diode array detector and high resolution mass spectrometry.

CONCLUSIONS: Hydroxylation, epoxidation, aromatization and GSH conjugation were the main metabolic pathways of senkyunolide A. This study provides an overview of the metabolic profiles of senkyunolide A, which is helpful for us to understand the action of this compound.
PMID: 32663340 [PubMed - as supplied by publisher]

Source: Rapid Communications in Mass Spectrometry : RCM - July 13, 2020 Category: Chemistry Authors: Zhang H, Liu C, Wang M, Sui Y Tags: Rapid Commun Mass Spectrom Source Type: research