Immunity to commensal skin fungi promotes psoriasiform skin inflammation [Immunology and Inflammation]
Under steady-state conditions, the immune system is poised to sense and respond to the microbiota. As such, immunity to the microbiota, including T cell responses, is expected to precede any inflammatory trigger. How this pool of preformed microbiota-specific T cells contributes to tissue pathologies remains unclear. Here, using an experimental...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Charlotte Hurabielle, Verena M. Link, Nicolas Bouladoux, Seong-Ji Han, Eric Dean Merrill, Yaima L. Lightfoot, Nickie Seto, Christopher K. E. Bleck, Margery Smelkinson, Oliver J. Harrison, Jonathan L. Linehan, Samira Tamoutounour, Michail S. Lionakis, Mari Tags: Biological Sciences Source Type: research