Maturation of the functional mouse CRES amyloid from globular form [Biophysics and Computational Biology]

The epididymal lumen contains a complex cystatin-rich nonpathological amyloid matrix with putative roles in sperm maturation and sperm protection. Given our growing understanding for the biological function of this and other functional amyloids, the problem still remains: how functional amyloids assemble including their initial transition to early oligomeric forms. To...

Source: Proceedings of the National Academy of Sciences - July 13, 2020 Category: Science Authors: Aveline Hewetson, Nazmul H. Khan, Matthew J. Dominguez, Hoa Quynh Do, R. E. Kusko, Collin G. Borcik, Daniel J. Rigden, Ronan M. Keegan, R. Bryan Sutton, Michael P. Latham, Benjamin J. Wylie, Gail A. Cornwall Tags: Biological Sciences Source Type: research