Real-time monitoring of peroxiredoxin oligomerization dynamics in living cells [Biochemistry]

Peroxiredoxins are central to cellular redox homeostasis and signaling. They serve as peroxide scavengers, sensors, signal transducers, and chaperones, depending on conditions and context. Typical 2-Cys peroxiredoxins are known to switch between different oligomeric states, depending on redox state, pH, posttranslational modifications, and other factors. Quaternary states and their changes...

Source: Proceedings of the National Academy of Sciences - July 13, 2020 Category: Science Authors: Daniel Pastor–Flores, Deepti Talwar, Brandan Pedre, Tobias P. Dick Tags: Biological Sciences Source Type: research