It Is Time to Rethink Biomarkers for Surveillance of Small Bowel Neuroendocrine Tumors.

CONCLUSION: Although specific for progression, NKA was rarely elevated, limiting its usefulness. Pre- and postoperative PST and CgA correlated with disease burden and survival, with PST providing better discrimination of outcomes. During the follow-up period, use of PST most accurately detected progression. These results suggest that PST should replace CgA for SBNET surveillance. PMID: 32656719 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32656719?dopt=Abstract

Source: Ann Oncol - July 10, 2020 Category: Cancer & Oncology Authors: Tran CG, Sherman SK, Scott AT, Ear PH, Chandrasekharan C, Bellizzi AM, Dillon JS, O'Dorisio TM, Howe JR Tags: Ann Surg Oncol Source Type: research