Botulinum toxin therapy improves masseter spasticity in Amyotrophic Lateral Sclerosis.

Botulinum toxin therapy improves masseter spasticity in Amyotrophic Lateral Sclerosis.
Rev Neurol (Paris). 2020 Jul 08;:
Authors: Mongin M, Debs R, Le Forestier N, Lenglet T, Salachas F, Pradat PF, Amador MD, Bruneteau G, Degos B
Abstract
Fifteen ALS patients, with troublesome symptoms linked to masseter spasticity, benefited from BoNT-A injections in each masseter. Based on the medical records of patients, the effect of the first injection was assessed one month later. We retrospectively collected information for 12 patients. Eight of them reported a beneficial effect after the injection for the following symptoms: trismus, tongue, lip and cheek biting, and jaw clonus. Five patients indicated that dental care was easier after injection. Our study showed that injections of BoNT-A unequivocally reduced masseter spasticity in ALS patients who subsequently enjoyed greater comfort in their daily living.
PMID: 32653215 [PubMed - as supplied by publisher]

Source: Revue Neurologique - July 13, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research