Gene-modified exosomes protect the brain against prolonged deep hypothermic circulatory arrest.

CONCLUSIONS: Exosomes from MSCs conduct powerful neuroprotection against cerebral injury induced by DHCA, which can be further enhanced by genetic modification of the exosomes to overexpress miR-214. PMID: 32652066 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32652066?dopt=Abstract

Source: The Annals of Thoracic Surgery - July 7, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Shi J, Jiang X, Gao S, Zhu Y, Liu J, Gu T, Shi E Tags: Ann Thorac Surg Source Type: research