COVID-19 and gastroenterology: clinical insights and recommendations for gastroenterology care providers.
COVID-19 and gastroenterology: clinical insights and recommendations for gastroenterology care providers. Scand J Gastroenterol. 2020 Jul 10;:1-7 Authors: Niriella MA, De Silva AP, Liyanage KI, Sarin SK, de Silva HJ Abstract While the COVID-19 pandemic evolves, we are beginning to understand the role the gastrointestinal tract plays in the disease and the impact of the infection on the care of patients with gastrointestinal (GI) and liver diseases. We review the data and understanding around the virus related to the digestive tract, impact of the pandemic on delivery of GI services and daily gastroenterology clinical practice, and the effects on patients with pre-existing GI diseases. PMID: 32650675 [PubMed - as supplied by publisher]
Coronavirus disease 2019 (COVID-19) is caused by the highly contagious zoonotic coronavirus SARS-CoV-2. The first cases of the disease were reported in China in December 2019; in the following months, the infection spread across the world, and by March 2020, it had been declared a global pandemic by the World Health Organization. To contain the spread of the infection, emergency measures, ranging from various degrees of social distancing to complete lockdowns have been adopted in different countries at different times.
During the recent outbreak of COV-SARS 2 infection, most hospitals in Italy as well as in almost every country of the world have been forced to reallocate their resources to cope with the huge flow of patients in need of hospitalization and even intensive care for respiratory symptoms.
This study was the first to demonstrate a causal relationship between glial senescence and neurodegeneration. In this study, accumulations of senescent astrocytes and microglia were found in tau-associated neurodegenerative disease model mice. Elimination of these senescent cells via a genetic approach can reduce tau deposition and prevent the degeneration of cortical and hippocampal neurons. Most recently, it was shown that clearance of senescent oligodendrocyte progenitor cells in AD model mice with senolytic agents could lessen the Aβ plaque load, reduce neuroinflammation, and ameliorate cognitive deficits. ...
The emergence of the COVID-19 pandemic, which started in Wuhan in 2019 changed the world and created several challenges to healthcare services. In preparation for expected increased numbers of patients with severe respiratory failure, many hospitals across the globe have intentionally reduced non-emergent procedures and hospitalizations to assure that initially scarce personal protective equipment was available and to preserve the different levels of hospital capacity. During this period, some studies reported reduced numbers of hospital admissions across different areas -from cirrhosis to heart failure [1 –4].
on March 11, 2020 the World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) a pandemic.1 Worldwide, clinicians of all specialties started to deal with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) and most of the efforts have been focused on the fight against this enemy. However, other diseases have not stopped to affect our patients and we confronted with the difficulties to provide the best care to patients with gastrointestinal diseases during this pandemic.
The COVID-19 pandemic had a huge impact on national and regional health systems. The impact of SARS-CoV-2 on the quality of care for patients with liver disease is still unknown.
Patients with COVID-19 may develop abnormal liver function and it's important to consider the potential impact of COVID-19 on the liver, especially in the Asia-Pacific region where chronic liver diseases are prevalent, say the authors of a position statement.Reuters Health Information
Authors: Konturek PC, Harsch IA, Neurath MF, Zopf Y Abstract Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV2) outbreak is the most dramatic event since World War II. Originating as a cluster of unexplained cases of pneumonia, it turned out that this viral disease termed COVID-19 is not only a respiratory infection, but a systemic disease associated with a number of extrapulmonary complications. One of the medical disciplines that is strongly affected by this viral infection is gastroenterology. COVID-19 causes in some patients typical symptoms of enteritis such as diarrhea or abdominal pain. There is als...
In the first months of 2020 the world faced a viral respiratory disease outbreak related to coronavirus SARS-CoV-2, which was declared a pandemic by the World Health Organization (WHO) on March 31st. To date nearly 4 million cases have been documented and a quarter of a million deaths reported globally.