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We thank Drs Driul and Londero for their letter regarding our article. In our study, we used birth certificate data to evaluate the effect of periconception smoking on birth defect risk and found that smoking in the 3 months leading up to pregnancy was associated with a modestly increased risk of gastroschisis. As mentioned in our study, although birth certificate data is a robust, high-quality data resource, one of its inherent limitations is that it does not include information about maternal alcohol or any other drug use.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Letter to the Editors Source Type: research