Evaluation of sample size for laboratory detection during HAdVs outbreaks in China: a systematic review and model research.

Evaluation of sample size for laboratory detection during HAdVs outbreaks in China: a systematic review and model research. Soc Work Public Health. 2020 Jul 10;:1-12 Authors: Wang J, Yue Y, Zhao Y, Ouyang X, Zhang H, Ding Z, Song W, Shi M, Li X, Li Q Abstract Human adenovirus infection is a common cause of upper and lower respiratory illness and easily breaks out in schools and the army. In an adenovirus epidemic, a large number of samples would be collected for laboratory diagnosis, and it is urgent to optimize the current sampling strategy. We researched the application of laboratory detection in the adenovirus epidemic and optimized the range of laboratory pathogen detection in the adenovirus epidemic by summarizing previous theoretical achievements, research reports, and experts' opinions and by using mathematical model tools. Under certain assumptions, a susceptible-infectious-quarantined-recovered (SIQR) model was established to describe the adenovirus epidemic and optimize the range of laboratory pathogen detection. Some standards and implementation rules suggest that when the number of cases is less than 10 or 20, all patients should be sampled for laboratory examination, and when the number of cases is more than 10 or 20, at least 10 or 20 samples should be collected. In practice, the sampling range can be appropriately expanded. A total of 21 studies were analyzed, and the sampling rate of adenovirus infection was 31% (95%C...
Source: Social Work in Public Health - Category: International Medicine & Public Health Tags: Soc Work Public Health Source Type: research