Impact of Non-steroidal Anti-inflammatory Drugs on Recurrence and Survival after Melanoma Surgery: A Cohort Study.

Impact of Non-steroidal Anti-inflammatory Drugs on Recurrence and Survival after Melanoma Surgery: A Cohort Study. Cancer Invest. 2020 Jul 09;:1-33 Authors: Araujo BLC, de Oliveira JL, Rezende JFN, Noguera WS, de Melo AC, Thuler LCS Abstract The aim of the study was to investigate if there was an association between intraoperative NSAID use and recurrence or survival. A cohort of patients who underwent sentinel lymph node biopsy for the treatment of cutaneous melanoma was retrospectively recruited. After applying inclusion and exclusion criteria, 516 were included (NSAIDs =307). The 10-year melanoma-specific survival was 63.2%. Log rank test showed no statistically significant differences in time to treatment failure, melanoma-specific survival, disease-free survival, and overall survival between the study groups. The current study did not support the use of intraoperative NSAIDs in preventing death or recurrence in patients with melanoma. PMID: 32643437 [PubMed - as supplied by publisher]
Source: Cancer Investigation - Category: Cancer & Oncology Tags: Cancer Invest Source Type: research