Grape Seed Extract-Soluplus Dispersion and its Antioxidant Activity.

Conclusions: The main reason for excellent scavenging activity of the formulations can be attributed to the presence of monomeric, dimeric, oligomeric procyanidins and the phenolic group. The present work denotes that GSE constitutes a good source of PC's and will be useful in the prevention and treatment of free radical related diseases. HighlightsGrape seed extract and soluplus nanodispersion was prepared by freeze drying methodThe particle size of GSE-SOLU dispersion was 69.9 nm with zeta potential of -82.1mVThe formulation FIII showed highest radical scavenging activity of 96.7%ABTS, FRAP, linoleic model exhibited dose-dependent scavenging activityHigher scavenging activity is due to the presence of proanthocyanidins. PMID: 32643446 [PubMed - as supplied by publisher]
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research