Outcomes of autologous non-cultured melanocyte keratinocyte transplantation in vitiligo and nevus depigmentosus.
Conclusion: MKTP is a safe and effective method for treating refractory vitiligo and nevus depigmentosus in Thai patients. PMID: 32643482 [PubMed - as supplied by publisher]
This article reports a case of the disease caused by mites of the species Dermanyssus gallinae. Increasingly, the agents that cause this disease are found in urban environments, increasing the incidence of people affected by the disease. This dermatosis has a self-limiting clinical picture and the treatment is done with the use of topical corticosteroids and oral antihistamines.
CONCLUSION: Single follicle transplantation was an alternative effective choice for treatment of vitiligo. The skin implanted with follicle with unintact hair bulb was less hairy. PMID: 32530337 [PubMed - as supplied by publisher]
Condition: Vitiligo Interventions: Procedure: MKTP with Surgical blade; Device: MKTP with Negative Pressure Instrument; Device: Suction blister grafting without cell dissociation Sponsor: University of California, Irvine Recruiting
To the Editor: Vitiligo remains a major challenge in dermatology, and many patients experience an incomplete therapeutic response to conventional phototherapy.1 Thus, various surgical interventions have been developed. In particular, noncultured melanocyte-keratinocyte transplantation (MKTP) has recently gained popularit y because it can treat a large area at once.2 However, this procedure does not always achieve complete repigmentation after a single session.3 If the remaining lesion is small and scattered, it may not be practical to repeatedly apply noncultured MKTP, considering the time and effort required for th e surgery.
Conclusions: The results of our study show that transplantation of autologous hair follicle cells is a simple and effective method to treat patients with stable vitiligo. Hair follicles (especially the outer root sheath) harbor many melanocytes with potential proliferative ability. Limitations: There are a few limitations of the present study: a small sample size, a short follow-up period, no cell counting or viability testing.
Condition: Vitiligo Interventions: Procedure: Melanocyte-Keratinocyte Transplantation and Ultraviolet Lamp (UVA); Device: RECELL 1:5 and Ultraviolet Lamp (UVA); Device: RECELL 1:10 and Ultraviolet Lamp (UVA); Device: RECELL 1:20 and Ultraviolet Lamp (UVA) Sponsor: Avita Medical Not yet recruiting