Increased Biologic Utilization in Latino Patients with Psoriasis.

Conclusions: Hispanic/Latino ethnicity and private insurance status are independent predictors of biologic utilization, suggesting that biologic mechanisms may influence the increased use of biologics in Latinos with psoriasis. PMID: 32643972 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research

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AbstractActivated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of intracellular granule components that function by capturing and destroying microbes, including viral, fungal, bacterial, and protozoal pathogens. The positive effects of pathogen control are countered by pro-inflammatory effects as demonstrated in a variety of diseases. Components of NETS are non-specific, and other than controlling microbes, they cause injury to surrounding tissue by themselves or by increasing the pro-inflammatory resp...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Conclusion: The guselkumab had excellent efficacy and great safety in moderate-to-severe plaque psoriasis, but long-term safety remained to be determined. PMID: 32724829 [PubMed - in process]
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
FRIDAY, July 31, 2020 -- Thyroid dysfunction in patients with psoriasis may be associated with inflammation caused by psoriasis, according to a study published online June 22 in the Journal of Dermatology. Jianfeng Zheng, from the Tongji University...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Conclusions and Implications: Direct and indirect comparisons and integrated results suggested that the 3 anti- tumor necrosis factor -α biologics (GOL, ETN, and IFX) can be considered the best treatments for PsA after comprehensive consideration of efficacy and safety.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
FDA Approves Wynzora Cream for Adults with Plaque Psoriasis Plaque psoriasis is a chronic skin condition often found on the elbows, knees, scalp and lower back. It is characterized by raised, red lesions with a silvery white scale that may itch,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Conclusions: The results of this study revealed significantly increased risk of both prevalent and incident uveitis among patients with psoriasis. PMID: 32724820 [PubMed - as supplied by publisher]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
This study revealed that AMPs and AVPs are two important functional protein clusters altering innate immune in psoriatic epidermis. OAS2 is a novel potential sensitive biomarker, which could predict the severity and activity of psoriasis, and could also be used as an indicator to evaluate or monitor the efficacy of clinical treatment.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Psoriasis is a chronic, immune-mediated, systemic, inflammatory disorder characterized by skin plaques and, often, nail disease and arthritis that contribute to reduced quality of life. Psoriatic arthritis —a heterogeneous, inflammatory, musculoskeletal disease that can cause permanent damage to both peripheral and axial joints—is the most common comorbidity of psoriasis. Axial disease occurs in 25% to 70% of patients with PsA, with some patients exclusively experiencing axial joint involvement. E arly therapeutic intervention is important for preventing permanent joint and spine damage and loss of functionality in these patients.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Tags: Review Source Type: research
Simultaneous use of FDG-18 and 68Ga-citrate PET/CT for the differential diagnosis of sarcoidosis and malignant disease. Monaldi Arch Chest Dis. 2020 Jul 29;90(3): Authors: Tetikkurt C, Sayman H, Dedeoglu SE, Kubat B, Tetikkurt S Abstract A 67-year-old male presented with cutaneous rash, lassitude and fatigue of three weeks. Personal history included psoriasis and sarcoidosis. Physical examination revealed macular rash on the anterior chest wall. Laboratory results were within normal limits. Chest X-ray showed normal findings. Pulmonary function tests demonstrated a mild obstructive pattern and a mild d...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Conditions:   Psoriasis Vulgaris;   Rheumatoid Arthritis;   Fibrosis, Liver Intervention:   Sponsor:   The University of Hong Kong Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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