Detection of Pseudorabies Virus Antibodies in Human Encephalitis Cases.

Detection of Pseudorabies Virus Antibodies in Human Encephalitis Cases. Biomed Environ Sci. 2020 Jun 20;33(6):444-447 Authors: Li XD, Fu SH, Chen LY, Li F, Deng JH, Lu XC, Wang HY, Tian KG Abstract Pseudorabies virus (PRV), a veterinary pathogen that infects domestic animals as well as wild animals such as wild boar and feral swine, was recently reported to infect human and led to endophthalmitis and encephalitis. A retrospective seroepidemiologic survey was conducted using 1,335 serum samples collected from patients with encephalitis and ELISA positive rates were 12.16%, 14.25%, and 6.52% in 2012, 2013, and 2017, respectively. The virus neutralizing antibody titers of positive samples correlated well with ELISA results. The pseudorabies virus antibody positive rate of patients with encephalitis were higher than that of healthy people in 2017. The above results suggest that some undefined human encephalitis cases may be caused by PRV infection. PMID: 32641207 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - Category: Biomedical Science Authors: Tags: Biomed Environ Sci Source Type: research