Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis.

This study for the first time uncovered some of the early molecular and cellular events by which estrogen disrupts testicular differentiation and causes feminization in X. laevis. These new findings improve our understanding of the mechanisms by which estrogenic EDCs disrupt testicular differentiation in vertebrates. PMID: 32645606 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32645606?dopt=Abstract

Source: Aquatic Toxicology - June 29, 2020 Category: Toxicology Authors: Li Y, Shen Y, Li J, Cai M, Qin Z Tags: Aquat Toxicol Source Type: research