Effects of anatomical location on in  vivo percutaneous penetration in man.

CONCLUSIONS: Regional variability in chemical and drug absorption is of clinical and pharmacological significance. More studies determining in vivo percutaneous absorption in man are necessary to further understand the role of regional variation, the mechanisms involved, and how to derive reliable formulas for extrapolating flux from one anatomic site to the next, often required for risk assessments. PMID: 32643443 [PubMed - as supplied by publisher]
Source: Cutaneous and Ocular Toxicology - Category: Toxicology Authors: Tags: Cutan Ocul Toxicol Source Type: research