Cell death in the gut epithelium and implications for chronic inflammation

Nature Reviews Gastroenterology & Hepatology, Published online: 10 July 2020; doi:10.1038/s41575-020-0326-4Evidence points to a crucial role of necroptosis and pyroptosis as important modes of programmed cell death in the intestine in addition to apoptosis. This Review discusses advances in our understanding of apoptosis, necroptosis and pyroptosis as major cell death pathways that can result in pathophysiological outcomes.

Source: Nature Reviews Gastroenterology and Hepatology - July 9, 2020 Category: Gastroenterology Authors: Jay V. Patankar Christoph Becker Source Type: research