Pericardial Effusion Associated with Diazoxide Treatment for Congenital Hyperinsulinism

Conclusion: Patients on long-term diazoxide treatment may be at risk of pericardial effusion, the timing and significance of which is unpredictable. The duration of diazoxide treatment before presentation of pericardial effusion varied in our patients from weeks to years. We advise serial echocardiography 1 –2 months after commencement of diazoxide and annually thereafter.Horm Res Paediatr
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research