Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin

ConclusionsOur assay demonstrated high diagnostic sensitivity and specificity for detection of clarithromycin and levofloxacin resistantH. pylori. Based on proven accuracy, together with high efficiency, scalability and low cost, our assay has useful clinical utility for rapid diagnosis of clarithromycin and levofloxacin resistantH. pylori infections. Our assay results will provide patients with a clear diagnosis, enabling the treating clinician to administer the most effective antibiotic regimen to help the clear the infection.
Source: Gut Pathogens - Category: Microbiology Source Type: research