Identification of TGF β signatures in six murine models mimicking different osteoarthritis clinical phenotypes

TGF β is a key player in cartilage homeostasis and OA pathology. However, few data are available on the role of TGFβ signalling in the different OA phenotypes. Here, we analysed the TGFβ pathway by transcriptomic analysis in six mouse models of OA.

Source: Osteoarthritis and Cartilage - July 8, 2020 Category: Rheumatology Authors: Marie Maumus, Dani èle Noel, Hang Korng Ea, David Moulin, Maxime Ruiz, Eric Hay, Xavier Houard, Damien Cleret, Martine Cohen-Solal, Claire Jacques, Jean-Yves Jouzeau, Marie-Hélène Lafage-Proust, Pascal Reboul, Jérémie Sellam, Claire Vinatier, Franço Source Type: research