Cancers, Vol. 12, Pages 1855: Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features

Cancers, Vol. 12, Pages 1855: Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features Cancers doi: 10.3390/cancers12071855 Authors: Rene Wei-Jung Chang Shu-Lin Chuang Chen-Yang Hsu Amy Ming-Fang Yen Wendy Yi-Ying Wu Sam Li-Sheng Chen Jean Ching-Yuan Fann Laszlo Tabar Robert A. Smith Stephen W. Duffy Sherry Yueh-Hsia Chiu Hsiu-Hsi Chen The aim was to evaluate how the inter-screening interval affected the performance of screening by mammographic appearances. This was a Swedish retrospective screening cohort study with information on screening history and mammography features in two periods (1977–1985 and 1996–2010). The pre-clinical incidence and the mean sojourn time (MST) for small breast cancer allowing for sensitivity by mammographic appearances were estimated. The percentage of interval cancer against background incidence (I/E ratio) was used to assess the performance of mammography screening by different inter-screening intervals. The sensitivity-adjusted MSTs (in years) were heterogeneous with mammographic features, being longer for powdery and crushed stone-like calcifications (4.26, (95% CI, 3.50–5.26)) and stellate masses (3.76, (95% CI, 3.15–4.53)) but shorter for circular masses (2.65, (95% CI, 2.06–3.55)) in 1996–2010. The similar trends, albeit longer MSTs, were also noted in 1977&...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research