Does sub-culturing of positive MRSA blood cultures affect vancomycin MICs?

Conclusion. Our results reveal a trend towards lower MICs after positive blood culture isolates are sub-cultured. Some clinical failures among MRSA infections treated with VAN may result from this phenomenon. PMID: 32639226 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32639226?dopt=Abstract

Source: Journal of Medical Microbiology - July 7, 2020 Category: Microbiology Authors: Kanesaka I, Ito T, Shishido R, Nagashima M, Kanayama Katsuse A, Takahashi H, Fujisaki S, Kobayashi I Tags: J Med Microbiol Source Type: research