Animal models of spinal injury for studying back pain and SCI

Publication date: Available online 8 July 2020Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Shakti Goel, Vicky Varghese, Tyfik Demir
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research

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Publication date: Available online 25 July 2020Source: NeuroImage: ClinicalAuthor(s): Eunhee Park, Hyunsil Cha, Eunji Kim, Yu-Sun Min, Ae Ryoung Kim, Hui Joong Lee, Tae-Du Jung, Yongmin Chang
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
With remote work becoming a widespread option during the Covid-19 pandemic, it ’s important to have the tools and advice to build a home office that will serve you best to get your job done. While many employees adapt to remote work, companies are creating programs and methods to make it easier for their employees to function.  To protect your body and increase product ivity, it’s important to have a desk and chair that support your spine which will minimize neck and back pain. Since we spend…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
DiscussionRecruitment began in February 2017 and will continue through 2019.Trial registrationClinicaltrials.govNCT03014583. Registered on 9 January 2017.
Source: Trials - Category: Research Source Type: clinical trials
We present the case of a 59-year-old woman admitted to the emergency department with confluent abscess formations of autochthonous back muscles and staphylococcal sepsis caused by injection therapy performed by a general practitioner for LBP. The findings of this case report emphasize a careful selection of patients for this type of treatment and a multidisciplinary approach to treatment of LBP.
Source: Wiener Medizinische Wochenschrift - Category: General Medicine Source Type: research
In this study, the relationship between P2X7R activation and p38 phosphorylation in the dorsal root ganglion (DRG) and spinal dorsal horn (SDH) in the development and maintenance of BTZ-induced neuropathic pain was elucidated. The results showed that BTZ increased mechanical thresholds in rats, accompanied with upregulation of P2X7R expression and p38MAPK phosphorylation, indicating that P2X7R and p38MAPK are key molecules in the development and maintenance of BTZ-induced neuropathic pain. Inhibiting p38MAPK phosphorylation with SB203580 resulted in downregulation of P2X7R expression levels. Inhibition of P2X7R with Brilli...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
The other week, my husband and I were driving home after visiting a beloved family member who is struggling with the excruciating pain and to-the-bone weariness of cancer. As our car lugged down the highway, I thought about the ongoing cruelty of our world: the ravages of disease and war, the current pandemic, the never-ending inhumanity, inequality, and brutality, as well as the general disregard to our earth and the innocent creatures who are clinging to survive on it. (And, yes, I do realize that I’m just as guilty as the masses in spewing out pollution by the simple fact that I drive a car). I held back tears, an...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Death & Dying Depression Grief and Loss Inspiration & Hope Personal Cancer Optimism Source Type: blogs
Curious how docs out there deal with “ultra-frequent fliers.” First a story. We have a guy, parapalegic after an MVC, wheelchair bound, who has had 16 ED visits this week alone. Over the last few years hear had close to 500 discrete visits. This week he was here for abdominal pain, discharged, back 20 minutes later with chest pain, back 8 hours later with back pain, slept on the street corner in his wheel chair, came back in the next day for fever, discharged, came back the next day... ULTRA-Frequent Fliers
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Emergency Medicine Source Type: forums
This week’s Psychology Around the Net takes a look at expert opinions on reopening schools for students’ mental health, new research on the impact of text messaging intervention as an add-on to existing mental health treatment plans, the differences in how female narcissists and male narcissists display narcissistic personality traits, and more. Be well, friends! Should Schools Reopen for Students’ Mental Health? Experts Weigh In: Mental health experts offer arguments for the importance of school for kids’ developmental health, with CDC Director Dr. Robert R. Redfield stressing, “It is critic...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Psychology Around the Net Adoption behavioral genetics coronavirus Narcissism narcissistic behavior Narcissistic Personality School Success texting intervention Source Type: blogs
Abstract Salmonella infection predominantly causes four clinical syndromes: enteric fever, gastroenteritis, bacteremia, and asymptomatic carrier state. Salmonella osteomyelitis is an extremely rare manifestation of salmonella infection except in children with hemoglobinopathies. Salmonella osteomyelitis has been reported to mostly affect the diaphysis of long bones and lumbar spine. Here, we describe a case of salmonella osteomyelitis of the right 6th rib in a 74-year-old woman who presented with breast pain, swelling, high fever and local heat. Her medical history showed myocardial infarction; namely, at the age ...
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research
In conclusion, ablation of GABAergic neurons induced alterations in spinal cord neuronal networks, providing novel insights into the pathophysiology of SBA-related pain-like complications. PMID: 32729294 [PubMed - in process]
Source: Folia Neuropathologica - Category: Pathology Authors: Tags: Folia Neuropathol Source Type: research
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