Treatment of intracerebral hemorrhage: Current approaches and future directions
Intracerebral hemorrhage (ICH) stands out among strokes, both for the severely morbid outcomes it routinely produces, and for the striking deficiency of defenses possessed against the same. The brain damage caused by ICH proceeds through multiple pathophysiological mechanisms, broadly differentiated into those considered primary, arising from the hematoma itself, and the secondary consequences of hematoma presence and expansion thereof. A number of interventions against ICH and its sequelae have been investigated (e.g., hemostatic therapies, blood pressure control, hematoma evacuation, and a variety of neuroprotective strategies), but conclusive demonstrations of clinical benefit have remained largely elusive.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Wenbo Zhao, Chuanjie Wu, Christopher Stone, Yuchuan Ding, Xunming Ji Tags: Review Article Source Type: research