Cancers, Vol. 12, Pages 1854: Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth —A Small Molecule Inhibitor, Berberine

In conclusion, our study suggests that GPT1-mediated alanine–glucose conversion may be a potential molecular target for HCC therapy. Further demonstration of BBR-mediated metabolic reprogramming of HCC would contribute to the development of this Chinese medicine-derived compound as an adjuvant therapy for HCC.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research