CircVCAN regulates the proliferation and apoptosis of osteoarthritis chondrocyte through NF- κB signaling pathway.

CONCLUSIONS: CircVCAN is overexpressed in OA tissues and cells. CircVCAN can affect the proliferation and apoptosis of OA chondrocytes by blocking the activation of the NF-κB signaling pathway. Thus, CircVCAN may be an important target molecule for OA treatment. PMID: 32633338 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research