MicroRNA-323-3p inhibits oxidative stress and apoptosis after myocardial infarction by targeting TGF- β2/JNK pathway.

CONCLUSIONS: MiR-323-3p was downregulated in ischemic myocardium and H2O2-treated H9c2 cells, and miR-323-3p overexpression reduced oxidative stress and apoptosis of cardiomyocytes. The protective function was achieved via regulation of TGF-β2/JNK pathway. PMID: 32633390 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research