The Runx1/Notch1 Signaling Pathway Participates in M1/M2 Microglia Polarization in a Mouse Model of Temporal Lobe Epilepsy and in BV-2 Cells.

In conclusion, Runx1 may play a critical role in the M2-to-M1 microglial phenotype shift via the Notch1 signaling pathway during epileptogenesis in a TLE mouse model and in BV-2 cells. PMID: 32632543 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32632543?dopt=Abstract

Source: Neurochemical Research - July 5, 2020 Category: Neuroscience Authors: Deng XL, Feng L, Wang ZX, Zhao YE, Zhan Q, Wu XM, Xiao B, Shu Y Tags: Neurochem Res Source Type: research