Adjusting lipid-water distribution coefficient of Iridium (III) complexes for enhancing its cellular penetration and treatment efficacy to antagonize cisplatin resistance in cervical cancer.

Dalton Trans., 2020, Accepted Manuscript DOI: 10.1039/D0DT02064H, PaperPengju Feng, Wei Huang, Zhen Chen, Liyuan Hou, Tianfeng Chen, Yiqun Li Effective design of metal complexes to manipulate its lipid-water distribution coefficient is an appealing strategy in improving its cellular penetration and treatment efficacy. Here, we conveniently synthesized three iridium (Ir)... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research