Post-mastectomy Radiotherapy Bolus Across the North and East London Radiotherapy Network

Purpose: Post-mastectomy radiotherapy decreases locoregional recurrence and reduces breast cancer mortality in a select group [1 –4]. Recurrence is most common at the chest wall, and bolus is used to increase skin surface dose [1,2]. Studies have shown huge variability in bolus use post-mastectomy, with no proven optimum regimen [1,2,5]. When using skin bolus, thickness and frequency of use increases skin toxicity [1,2,6]. Severe toxicity including pain, or moist desquamation, can lead to treatment cessation, resulting in inferior local control [1,2].

Source: Clinical Oncology - July 8, 2020 Category: Radiology Authors: E. Scott, S. Needleman Source Type: research