HCV/BVDV Chimeric Genomes and Uses Thereof

The current invention provides nucleic acid sequences comprising chimeric viral genome of hepatitis C Virus (HCV) and bovine viral diarrhea viruses (BVDV). The chimeric viruses are produced by replacing the structural region or a structural gene of an infectious BVDV clone with the corresponding region or gene of an infectious HCV. It covers the use of these sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV.IC: NIAIDNIH Ref. No.: E-102-1999-0TAB No: TAB-489Provider Technology ID: 489Updated On: Jul 6, 2020Date Published: Monday, July 6, 2020Patent Application: 10/009,011PCT/US00/1552760/137,817Patent Authority: USEIRPCTUSPatent Number: 7,009,044Lead Inventor: Inventor IC: NIAIDNIAIDNIAIDNIAIDLPM FIrst Name: PeterLPM Last Name: SoukasLPM Address: 5601 Fishers Lane, Suite 6D (MSC 9804)LPM City: RockvilleInv Is lead: LPM Zip: 20892-9804LPM State: MDLPM Phone: [phone]LPM Email: [e-mail] Suffix: J.D.LPM Organization: NIH Office of Technology TransferLPM Fax: [phone]DTDT Classification: Infectious DiseasesVaccinesViralResearch MaterialsDTDT Description: Infectious DiseasesInfectious Diseases - VaccinesInfectious Diseases - Vaccines - ViralInfectious Diseases - Research...

Source: NIH OTT Licensing Opportunities - July 6, 2020 Category: Research Authors: ott-admin Source Type: research