Dosimetric benefits of gantry-static couch-motion (GsCM) technique for breast boost radiation therapy: Reduced dose to organs-at-risk and improved dosimetric indices.

Dosimetric benefits of gantry-static couch-motion (GsCM) technique for breast boost radiation therapy: Reduced dose to organs-at-risk and improved dosimetric indices. J Appl Clin Med Phys. 2020 Jul 05;: Authors: Gill GS, Jakubovic RY, Baker J, Button T, Chang J Abstract To evaluate the clinical feasibility and dosimetric benefits of a novel gantry-static couch-motion (GsCM) technique for external beam photon boost treatment of lumpectomy cavity in patients with early-stage breast cancer in comparison to three-dimensional conformal radiotherapy (3D-CRT), wedge pair in supine position (WPS), and wedge pair in decubitus position (WPD) techniques. A retrospective review was conducted on breast patients (right breast, n = 10 and left breast, n = 10) who received 10 Gy boost after 50 Gy to whole breast. The treatment plans were generated using an isocentric-based GsCM technique (a VMAT type planning approach) integrating couch rotational motion at static gantry positions. Static fields for each tangential side were merged using a Matlab® script and delivered automatically within the Varian TruebeamTM STx in Developer Mode application as a VMAT arc (wide-angular medial and short-angular lateral arcs). The dosimetric accuracy of the plan delivery was evaluated by ion chamber array measurements in phantom. For both right and left breast boost GsCM, 3D-CRT, WPS, and WPD all provided an adequate coverage to PTV. GsCM significantly reduce...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: J Appl Clin Med Phys Source Type: research