Detection of sub-centimeter lesions using digital TOF-PET/CT system combined with Bayesian penalized likelihood reconstruction algorithm

ConclusionThe BPL in the digital TOF-PET/CT scanner improved the quantitation and detectability of sub-centimeter spheres compared with OSEM-based reconstruction. Optimization of theβ value in BPL might allow the detection of lesions  ≤ 6 mm, although detectability depended on the TBR of lesions. Aβ value of 200 seemed optimal for detecting sub-centimeter lesions.
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research