Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease.

Translational Research in Culture: AADAC, Diabetes, and Cardiovascular Disease.
Cell Stem Cell. 2020 Jul 02;27(1):6-7
Authors: Misra A, Fisher EA
Abstract
Many type 2 diabetes patients develop cardiovascular disease (CVD) while some are protected. Toyohara et al. (2020) find that elevated arylacetamide deacetylase (AADAC) expression in vascular smooth muscle cells (dVSMCs) differentiated from patient-derived induced pluripotent stem cells is associated with cardioprotection. AADAC overexpression alters multiple dVSMC properties and decreases murine CVD.
PMID: 32619519 [PubMed - as supplied by publisher]

Source: Cell Stem Cell - July 1, 2020 Category: Stem Cells Authors: Misra A, Fisher EA Tags: Cell Stem Cell Source Type: research