Expert Opinion on the Management and Follow-up of Uveitis Patients during SARS-CoV-2 Outbreak.

Expert Opinion on the Management and Follow-up of Uveitis Patients during SARS-CoV-2 Outbreak. Expert Rev Clin Immunol. 2020 Jul 02;: Authors: Stanescu-Segall D, Sales de Gauzy T, Reynolds R, Faes L, Pohlmann D, Pakzad-Vaezi K, Ting D, Saadoun D, Ambati J, Loewenstein A, Bodaghi B, de Smet MD, Touhami S Abstract INTRODUCTION: Routine medical and ophthalmic care is being drastically curtailed in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Uveitis patients require particular attention because of their theoretical risk of viral infection, in the context of therapeutic immunosuppression. AREAS COVERED: This collaborative work proposes practical management and follow-up criteria for uveitis patients in the context of the ongoing SARS-CoV-2 pandemic. EXPERT OPINION: Management should proceed as usual when access to healthcare is possible in patients who do not belong to a group at high risk of severe SARS-CoV-2 infection; and in uncontrolled uveitis cases. In case of reduced access to eye clinics or high risk of SARS-CoV-2 infection, patients' management should be stratified based on their clinical presentation. In non-severe uveitis cases, the use of systemic steroids should be avoided, and local steroids preferred whenever possible. In uncontrolled situations where there is real risk of permanent visual loss, high-dose intravenous steroids and/or systemic immunosuppressants and/or biotherapies can be admin...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research

Related Links:

The COVID-19 crisis has unleashed a plastic pandemic, reversing the achievement of a decade of activism against single-use plastic worldwide, including Nepal. Credit: BIKRAM RAIBy Sonia Awale and Ramesh KumarKATHMANDU, Aug 3 2020 (IPS) The coronavirus pandemic was a respite for nature everywhere. The air was cleaner, trekking trails were pristine, the summit of Mt Everest was deserted, and worldwide carbon emission dipped by -26%. However, there are dark clouds in that silver lining. The COVID-19 crisis has unleashed a plastic pandemic, reversing the achievement of a decade of activism against single-use plastic worldwide,...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Environment Headlines Health COVID-19 Source Type: news
In this study, through a literature review and data collec tion, we focus on the selection and consideration of antitumor treatment strategies for advanced lung cancer during the coronavirus disease 2019 (COVID-19) epidemic.
Source: Medical Oncology - Category: Cancer & Oncology Source Type: research
Drug Res (Stuttg) DOI: 10.1055/a-1217-2397The current outbreak of novel Coronavirus Disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major pandemic situation and a catastrophe for humans. COVID-19 is a severe infectious disease particularly of the respiratory system characterized by fatal complications such as severe acute respiratory distress syndrome (SARS), pneumonia, cardiac arrhythmia, kidney failure/ multiple organ failure and even death. Since its discovery, the SARS-CoV-2 has spread across 213 countries or territories, causing mor...
Source: Drug Research - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research
In this study, we proposed a random walk model to identify the potential pathological mechanisms of COVID-19 on a virus-human protein interaction network, and we effectively identified a group of proteins that have already been determined to be potentially important for COVID-19 infection and for similar SARS infections, which help further developing drugs and targeted therapeutic methods against COVID-19. Moreover, we constructed a standard computational workflow for predicting the pathological biomarkers and related pharmacological targets of infectious diseases. PMID: 32685484 [PubMed - indexed for MEDLINE]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
ebbraio Coronaviruses have received global concern since 2003, when an outbreak caused by SARS-CoV emerged in China. Later on, in 2012, the Middle-East respiratory syndrome spread in Saudi Arabia, caused by MERS-CoV. Currently, the global crisis is caused by the pandemic SARS-CoV-2, which belongs to the same lineage of SARS-CoV. In response to the urgent need of diagnostic tools, several lab-based and biosensing techniques have been proposed so far. Five main areas have been individuated and discussed in terms of their strengths and weaknesses. The cell-culture detection and the microneutralization tests are still cons...
Source: Sensors - Category: Biotechnology Authors: Tags: Review Source Type: research
The U.S. domestic response to the COVID-19 pandemic thus far has been “weak,” Bill Gates believes. The Bill and Melinda Gates Foundation co-chair and Microsoft co-founder told TIME senior health correspondent Alice Park during a TIME100 Talks discussion on Thursday that he’d give the U.S.’s COVID-19 response, “on a relative and absolute basis, not a passing grade.” But, he added, the U.S.’s funding for vaccine and therapeutic research “has been the best in the world,” so if it coordinates to share resources globally, the U.S. could “potentially score the highest&...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 News Desk TIME100 Talks Source Type: news
By MICHEL ACCAD, MD With cases of COVID-19 either disappeared or rapidly diminishing from places like Wuhan, Italy, New York, and Sweden, many voices are speculating that herd immunity may have been reached in those areas and that it may be at hand in the remaining parts of the world that are still struggling with the pandemic.  Lockdowns should end—or may not have been needed to begin with, they conclude. Adding plausibility to their speculation is the discovery of biological evidence suggesting that prior exposure to other coronaviruses may confer some degree of immunity against SARS-CoV...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: COVID-19 Health Policy immunity MICHEL ACCAD Pandemic Source Type: blogs
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, with>365,000 cases in California as of 17 July 2020. We investigated the genomic epidemiology of SARS-CoV-2 in Northern California from late January to mid-March 2020, using samples from 36 patients spanning nine counties and the Grand Princess cruise ship. Phylogenetic analyses revealed the cryptic introduction of at least seven different SARS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washington state, with lack of a predominant lineage and lim...
Source: ScienceNOW - Category: Science Authors: Tags: Epidemiology, Virology reports Source Type: news
The ongoing coronavirus disease 2019 (COVID-19) pandemic has affected hundreds of thousands of people, including infants and children. We carried out a comprehensive literature review to identify the underlying mechanisms and risk factors for severe COVID-19 in children, in comparison with the other two coronavirus outbreaks in the past, SARS and MERS. Search in the Pubmed and Scopus databases to identify publications between February 26, 2020 and June 10, 2020 identified 23 relevant papers in English. Children have so far accounted for 1.7-2% of the diagnosed cases of COVID-19. They often have milder disease than adults, ...
Source: Pediatric Clinics of North America - Category: Pediatrics Authors: Source Type: research
Abstract Virus onslaughts continue to spread fear and cause rampage across the world every now and then. The twenty first century is yet again witnessing a gross global pandemic, Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Globally no vaccines or drug specific to COVID-19 is available. Corona viruses have been in mutual relationship with humans and other hosts over many decades though aggressive zoonotic strains have caused havoc. Zoonotic emergent corona viruses prior to SARS-COV-2 included severe acute respiratory syndrome coronavirus (SARS-CoV) and...
Source: European Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharmacol Source Type: research
More News: Allergy & Immunology | Coronavirus | COVID-19 | Opthalmology | Outbreaks | Pandemics | Respiratory Medicine | SARS