NMR spectroscopy in the conformational analysis of peptides: an overview.

CONCLUSION: NMR is a leading technique in the study of conformational preferences of small flexible peptides whose structure can be often only described by an ensemble of conformations. Although NMR studies of peptides can be easily and fast performed by canonical protocols established a few decades ago, more recently we have assisted to tremendous improvements of NMR spectroscopy to investigate instead large systems and overcome its molecular weight limit.
PMID: 32614739 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - July 1, 2020 Category: Chemistry Authors: Vincenzi M, Mercurio FA, Leone M Tags: Curr Med Chem Source Type: research