Hydralazine-Induced Isolated Lupus Nephritis.

Conclusion: Isolated renal disease induced by hydralazine as part of drug-induced lupus is uncommon. Our patient developed isolated classic lupus nephritis after hydralazine therapy with no associated systemic vasculitis. Treatment required stopping the hydralazine and initiating systemic immunosuppressive therapy to achieve complete remission. PMID: 32612474 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research

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Authors: Mendenhall E, Musau A, Bosire E, Mutiso V, Ndetei D, Rock M Abstract Type 2 diabetes mellitus is a condition that both results from and produces social and psychological suffering. As 'diabetes' increases among low income patients in poorer nations, new challenges arise that drive, co-occur, and result from the condition. In this article, we describe how social suffering produces diabetes by way of addressing the varied social, psychological, and biological factors that drive diabetes and are reflected in diabetes experiences among patients seeking care at a public hospital in Nairobi, Kenya. We recruited ...
Source: Anthropology and Medicine - Category: International Medicine & Public Health Tags: Anthropol Med Source Type: research
Authors: Marín-Sánchez A Abstract The basic clinical characteristics of the first 100 fatal cases from COVID-19 in Colombia were analyzed based on reports from the National Institute of Health (INS) since the beginning of the pandemic. Since the INS records do not include clinical variables of comorbidity in the total number of cases reported as positive, but only in patients with fatal outcome, comorbidities, age and sex available in the daily INS reports were reviewed. Their frequency was identified and mortality risk behavior for the analyzed variables was established and compared with the behavior...
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
Publication date: 1 December 2020Source: Carbohydrate Polymers, Volume 249Author(s): Shijie Dai, Shaozhong Liu, Chen Li, Zhifang Zhou, Zhimeng Wu
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: 1 December 2020Source: Carbohydrate Polymers, Volume 249Author(s): Shuxian Hu, Rei Kuwabara, Martin Beukema, Michela Ferrari, Bart J. de Haan, Marthe T.C. Walvoort, Paul de Vos, Alexandra M. Smink
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: September 2020Source: Biomedical Signal Processing and Control, Volume 62Author(s): Gayathri S., Varun P. Gopi, P. Palanisamy
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
CONCLUSIONS: The 'Spanner in the Works?' initiative was effective in reaching both healthy and at-risk rural men from a range of ages. SO WHAT?: Aligned with the National Men's Heath Strategy 2020-2030, this evidences that agricultural events are an effective social setting for the provision of health promotion to 'at risk' rural men. PMID: 32748496 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
Heart failure (HF) with reduced contractile function is a common and lethal syndrome in which the heart cannot pump blood to adequately meet bodily demands, resulting in high mortality despite the current standard of care. In modern societies, the most common drivers of HF are ischemic heart disease and hypertension. However, in a substantial subset of cases, patients present with dilated and poorly contracting hearts without evidence of common inciting stressors, a syndrome called dilated cardiomyopathy (DCM). Genome sequencing has identified a host of deleterious germline variants in key cardiomyocyte genes as causes of ...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Cachexia, a devastating wasting syndrome characterized by severe weight loss with specific losses of muscle and adipose tissue, is driven by reduced food intake, increased energy expenditure, excess catabolism, and inflammation. Cachexia is associated with poor prognosis and high mortality and frequently occurs in patients with cancer, chronic kidney disease, infection, and many other illnesses. There is no effective treatment for this condition. Hypothalamic melanocortins have a potent and long-lasting inhibitory effect on feeding and anabolism, and pathophysiological processes increase melanocortin signaling tone, leadin...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Publication date: Available online 12 August 2020Source: Microvascular ResearchAuthor(s): Sarah Zinn, Pieter Nelis, Katharina Minnebeck, Jens Hinder, Nicole Eter, Stefan-Martin Brand, Reinhold Gellner, Elena Vorona, Florian Alten, Boris Schmitz
Source: Microvascular Research - Category: Biochemistry Source Type: research
CONCLUSION: Community-based screening and facility-based screening were complementary methods in reaching different population groups at high risk of developing type 2 diabetes. Community screening in particular reached more hard-to-reach groups with unfavorable risk profiles, making it a critical strategy for T2D prevention. More men should be recruited to intervention studies and screening initiatives to achieve a gender balance. PMID: 32746747 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
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