Spontaneous Clearance After Relapse Following Direct-Acting Antiviral Treatment for Chronic HCV Infection

Direct-acting antivirals (DAAs) cure most cases of chronic hepatitis C virus (HCV) infections. However, a small percentage of patients relapse with reappearance of viremia after a full course of therapy. Although most who relapse require retreatment, some patients spontaneously clear HCV without additional therapy. We studied patients who relapsed with detectable HCV RNA after a full course of DAA therapy and then spontaneously cleared the HCV infection without retreatment.

Source: Clinical Gastroenterology and Hepatology - July 2, 2020 Category: Gastroenterology Authors: Hadi Kuriry, Julia Casey, Lisette Krassenburg, Danie La, Magdalena Kuczynski, Hemant Shah, Harry L.A. Janssen, Bettina E. Hansen, Jordan J. Feld Source Type: research