Low systemic vitamin D as a potential risk factor in primary open-angle glaucoma: a review of current evidence.

Low systemic vitamin D as a potential risk factor in primary open-angle glaucoma: a review of current evidence.
Br J Ophthalmol. 2020 Jun 30;:
Authors: Huynh B, Shah P, Sii F, Hunter D, Carnt N, White A
Abstract
Currently, intraocular pressure is the only modifiable risk factor for glaucoma; thus, identifying other modifiable determinants may have far-reaching outcomes. There has been increasing interest in vitamin D status and glaucoma pathogenesis as low vitamin D has been identified by some studies as an independent risk factor for glaucoma. Although the exact mechanism of vitamin D in glaucoma remains uncertain, there is sufficient evidence to continue research in this area. There is a potential physiological role for vitamin D as an anti-inflammatory agent in the oxidative stress-driven pathogenesis of primary open-angle glaucoma, and further studies are required to evaluate the temporal and causal relationship. Ocular vitamin D status in the tear, aqueous and vitreous fluid is a prospective gap in research.
PMID: 32606080 [PubMed - as supplied by publisher]

Source: The British Journal of Ophthalmology - June 29, 2020 Category: Opthalmology Authors: Huynh B, Shah P, Sii F, Hunter D, Carnt N, White A Tags: Br J Ophthalmol Source Type: research