Interaction between catechol ‐O‐methyltransferase polymorphism and childhood trauma in suicidal ideation of patients with post‐traumatic stress disorder

ConclusionOur results suggest that vulnerability to suicide could be increased in the Val/Val genotype ofCOMT rs4680 and the CC genotype of rs4633 in patients with PTSD. Moreover, PTSD group with high childhood emotional abuse demonstrated a significantly higher suicidal ideation than did those with low childhood emotional abuse.
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research