Coniferaldehyde attenuates Alzheimer's pathology via activation of Nrf2 and its targets

Conclusion: The experimental evidence overall indicated that Nrf2 activation may contribute to the potent anti-AD effects of CFA. With an excellent safety profile, further clinical investigation of coniferaldehyde might bring hope for AD prevention/therapy.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Yaqiong Dong, Tessandra Stewart, Lidan Bai, Xue Li, Ting Xu, Jeffrey Iliff, Min Shi, Danfeng Zheng, Lan Yuan, Taotao Wei, Xiaoda Yang, Jing Zhang Tags: Research Paper Source Type: research