ASIC1a induces synovial inflammation via the Ca2+/NFATc3/ RANTES pathway

Conclusion: ASIC1a induces synovial inflammation, which leads to the progression of RA. Our study reveals a novel RA inflammation regulatory mechanism and indicates that ASIC1a might be a potential therapeutic target for RA.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Yihao Zhang, Xuewen Qian, Xiaojuan Yang, Ruowen Niu, Sujing Song, Fei Zhu, Chuanjun Zhu, Xiaoqing Peng, Feihu Chen Tags: Research Paper Source Type: research