Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2

Conclusion: Our data have unveiled an essential role of BI1 as a master regulator of renal tubule function through sustaining mitochondrial localization of PHB2, revealing novel therapeutic promises against AKI.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Jin Wang, Pingjun Zhu, Ruibing Li, Jun Ren, Yingmei Zhang, Hao Zhou Tags: Research Paper Source Type: research