Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE-/- mice

Conclusions: Our study demonstrate that formononetin can substantially attenuate the development of atherosclerosis via regulation of interplay between KLF4 and SRA, which suggests the formononetin might be a novel therapeutic approach for inhibition of atherosclerosis.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Chuanrui Ma, Ronglin Xia, Shu Yang, Lipei Liu, Jing Zhang, Ke Feng, Yuna Shang, Jingtian Qu, Lingwei Li, Ning Chen, Shixin Xu, Wenwen Zhang, Jingyuan Mao, Jihong Han, Yuanli Chen, Xiaoxiao Yang, Yajun Duan, Guanwei Fan Tags: Research Paper Source Type: research