Novel ESCC-related gene ZNF750 as potential Prognostic biomarker and inhibits Epithelial-Mesenchymal Transition through directly depressing SNAI1 promoter in ESCC

Conclusion: Our results suggest that ZNF750 may act as a tumor suppressor by directly repressing SNAI1 and inhibiting EMT process in ESCC and other types of SCC.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Pengzhou Kong, Enwei Xu, Yanghui Bi, Xiaoqin Xu, Xue Liu, Bin Song, Ling Zhang, Caixia Cheng, Ting Yan, Yu Qian, Jian Yang, Yanchun Ma, Heyang Cui, Yuanfang Zhai, Binbin Zou, Xiangchen Liu, Yikun Cheng, Shiping Guo, Xiaolong Cheng, Yongping Cui Tags: Research Paper Source Type: research