Circular RNA SAMD4A controls adipogenesis in obesity through the miR-138-5p/EZH2 axis

Conclusions: CircSAMD4A regulated preadipocyte differentiation by acting as a miR-138-5p sponge, and thus increasing EZH2 expression. These results suggested that circSAMD4A can serve as a potential target for obesity treatments and/or as a potential prognostic marker for obese patients following bariatric surgery.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Yanjun Liu, Hongtao Liu, Yi Li, Rui Mao, Huawu Yang, Yuanchuan Zhang, Yu Zhang, Pengsen Guo, Dafang Zhan, Tongtong Zhang Tags: Research Paper Source Type: research