miR-182-3p/Myadm contribute to pulmonary artery hypertension vascular remodeling via a KLF4/p21-dependent mechanism
Conclusion: Our findings indicate the prognostic and therapeutic significance of miR-182-3p in PAH and provide a new regulatory model of the myeloid-derived miR-182-3p/Myadm/KLF4/p21 axis in PAH vascular remodeling.
Source: Theranostics - Category: Molecular Biology Authors: Lan Sun, Peirong Lin, Ying Chen, Haoying Yu, Shuyu Ren, Jingrong Wang, Liyun Zhao, Guanhua Du Tags: Research Paper Source Type: research