Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with 68Ga-PSMA-11-PET

Conclusions: PSMA-negative tumour area on IHC exhibited the strongest association with negative PSMA-PET scans, beside PSA-level and ADT. Even at very high PSA levels, PSMA-PET scans were negative in most of the patients with PSMA%neg ≥ 50%.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Daniela A. Ferraro, Jan H. R ü schoff, Urs J. Muehlematter, Benedikt Kranzb ü hler, Julian M ü ller, Michael Messerli, Lars Husmann, Thomas Hermanns, Daniel Eberli, Niels J. Rupp, Irene A. Burger Tags: Research Paper Source Type: research